Defended Theses

Ph.D. theses

Ljudmila Klepinina, 2021
Rearrangement of Energy Metabolism During Differentiation of Cancer Cells. Supervisor Tuuli Käämbre, Tallinn University of Technology, Department of Chemistry and Biotechnology.

Andre Koit, 2018. Malignant Transformation Causes Rearrangement of Energy Metabolism in Colorectal and Breast Cancers. Supervisors Tuuli Käämbre ja Vahur Valvere, Tallinn University of Technology, Department of Chemistry and Biotechnology.

Andrus Kaldma, 2017. Metabolic Remodeling of Human Colorectal Cancer: Alterations in Energy Fluxes. Supervisors Tuuli Käämbre ja Natalja Timohhina, Tallinn University of Technology, Department of Chemistry and Biotechnology.

Minna Varikmaa, 2013.  Structural and functional studies of mitochondrial respiration regulation in muscle cells. Supervisors Valdur Saks, Madis Metsis. Tallinn University of Technology, Faculty of Science, Department of Chemistry, Center for Biology of Integrated Systems.

Kersti Tepp, 2011. Molecular system bioenergetics of cardiac cells: Quantitative analysis of structure-function relationship. Supervisors Valdur Saks, Raivo Vilu. Tallinn University of Technology, Faculty of Science, Department of Chemistry.

Natalja Timohhina, 2011. Molecular system bioenergetics of the heart cells: Mitochondrial Interactosome. Supervisors Valdur Saks, Tuuli Käämbre. Tallinn University, Institute of Mathematics and Natural Sciences.

Tiia Anmann, 2007. Integrated and organized cellular bioenergetic systems in heart and brain. Supervisors Valdur Saks, Raivo Vilu. Tallinn University of Technology, Faculty of Science, Department of Chemistry.

Tuuli Käämbre, 2004. Intracellular energetic units: Structural and functional aspects. Supervisors Enn Seppet, Valdur Saks. Tartu University, Faculty of Medicine.

Toomas Tiivel, 2002. The role of the mitochondrial outer membrane in in vivo regulation of respiration in normal heart and skeletal muscle cells. (Étude contrôle de la respiration mitochondrial des cellules musculaires-rôle de la membrane externe). Supervisors Valdur Saks, André Rossi, Enn Seppet. Tallinn University of Technology, Joseph Fourier University (Grenoble, France).

Master’s theses

Leenu Reinsalu, 2020. Metabolic Reprogramming in Colorectal Cancer and Colon Polyps. Supervisors Tuuli Käämbre, Egle Rebane-Klemm, Tallinn University of Technology, Department of Chemistry and Biotechnology.

Sten Miller, 2020. Optimization and application of stable isotope mass spectrometry method to study breast cancer energy metabolism. Supervisors Aleksandr Klepinin, Tuuli Käämbre, Tallinn University of Technology, Department of Chemistry and Biotechnology.

Kaisa Kuus, 2018. Expression of pluripotency related marker proteins in human colorectal adenocarcinoma Caco2 cells. Supervisors Martin Pook, Aleksandr Klepinin, Ljudmila Klepinina, University of Tartu, Faculty of Science and Technology,
Institute of Molecular and Cell Biology.

Aivar Uus, 2016. Energiaülekande võrgustiku profiili arengulised ja vananemisega seotud muutused kardiomüotsüütides. Supervisors Kersti Tepp, Kairi Koort, Tallinn University, School of Natural Sciences and Health.

Aleksandr Klepinin, 2014. Comparative analysis of mitochondrial metabolism in differentiated and undifferentiated neuroblastoma cells. Supervisors Tuuli Käämbre, Igor Shevchuk. Tallinn University of Technology, Faculty of Science, Department of Gene Technology.

Aia Simm, 2011. Comparative bioenergetics of nerve cells. Supervisors Tuuli Käämbre, Tiit Land. Tallinn University, Institute of Mathematics and Natural Sciences.
Diploma for the Master thesis on health research on National Science Contest for university level students.

Merle Saaremäe, 2010. Expression and role of beta-tubulin isoforms in regulation of permeability of mitochondrial outer membrane. Supervisors Tuuli Käämbre, Sirje Rüütel Boudinot. Tallinn University of Technology, Faculty of Science, Department of Gene Technology.
Ist prize for the Master thesis on health research on National Science Contest for university level students.

Bachelor’s theses

Maari Tamm, 2013. Determination of the bioenergetic profile in Neuro-2a cells. Supervisors Kersti Tepp, Natalja Timohhina. Tallinn University, Institute of Mathematics and Natural Sciences.

Ott Kaljula, 2013. Determination of metabolic parameters of colorectal cancer in clinical samples. Supervisors Kersti Tepp, Natalja Timohhina. Tallinn University, Institute of Mathematics and Natural Sciences.

Tuuli Tamm, 2009. Regulation of mitochondrial respiration in cardiac cells in vivo. Supervisor Tuuli Käämbre. Tallinn University, Institute of Mathematics and Natural Sciences.

Aia Simm, 2008. The new procedure of preparation of cardiac myocytes. Supervisor Tuuli Käämbre. Tallinn University, Institute of Mathematics and Natural Sciences.

Priit Hani, 2007. Function of creatine kinase in heart muscle cells in intracellular energetic unit. Supervisor Tuuli Käämbre. Tallinn University, Institute of Mathematics and Natural Sciences.

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