Tuesday, 24 April
8:30 – 9:15 Registration & hanging posters
9:15 – 9:30 Opening
Chairs: Uwe Schlattner and Tuuli Käämbre
9:30 – 10:10 Invited speaker: Petras Dzeja – Phosphotransfer networks and metabolic signaling circuits
10:10 – 10:50 Invited speaker: Uwe Schlattner – The mitochondrial nucleoside diphosphate kinase NME4/NM23-H4 has dual functions in bioenergetics and signaling death decisions
10:50 – 11:20 Coffee break
11:20 – 12:00 Invited speaker: Maria Luisa Genova – Respiratory supercomplexes: physiological and pathological implications
12:00 – 12:30 Emirhan Nemutlu – 18O-assisted mass spectrometry for mitochondrial dynamics evaluation
12:30 – 12:45 Alexander Gritsuk – Mitochondrial oxidation in rat spleen following the short- and long-term dietary 137Cs intake
12:45 – 13:00 Alexander Koval – The eventual role of mitochondrial DNA guanine quadruplexes in sensitivity to ionizing radiation
13:00 – 14:00 Lunch & poster session
Chair: Emirhan Nemutlu
14:00 – 14:30 Invited speaker: Gennady Yegutkin – Cellular ATP turnover and its modulation during inflammation, hypoxia and tumorigenesis
14:30 – 14:50 Mart Roosimaa – Mitochondria-related molecular changes in sarcopenia
14:50 – 15:10 Sona Hubackova – Selective elimination of senescent cells by mitochondrial targeting is regulated via ANT2
15:10 – 15:40 Invited speaker: Marko Vendelin – Studies of creatine deficient mice: from respiration to EC coupling
15:40 – 16:10 Piotr Koprowski – Regulation of activity of mitochondrial potassium channels
16:10 – 16:30 Coffee break
16:30 – 18:30 Entertaining Old Town walking tour. Tour starts in front of the building of the Estonian Academy of Sciences (Kohtu str. 6) and ends in front of the restaurant Kaerajaan
18:30 Dinner in restaurant Kaerajaan (17 Town Hall Square)
Wednesday, 25 April
Chair: Jukka Kallijärvi
9:30 – 10:00 Invited speaker: Erich Gnaiger – Chemiosmotic control of the proton leak: the fundamental distinction of force and pressure
10:00 – 10:40 Invited speaker: Rafael Moreno-Sanches – Control of the NADPH supply and GSH recycling for oxidative stress management in hepatoma mitochondria
10:40 – 11:20 Invited speaker: Varda Shoshan-Barmatz – VDAC1 as a Target: Crossing the Aisle from Cancer to Neurodegeneration and Diabetes
11:20 – 11:50 Coffee break
11:50 – 12:30 Invited speaker: Vladimir Veksler – Mitochondria as a target for sex differences in pathologies
12:30 – 13:00 Invited speaker: Sara Rodriguez-Enriquez – Mitochondrial function as therapeutic target site for metastatic cancers
13:00 – 13:20 Andre Koit – Standard static markers do not explain breast cancer metabolic alterations
13:20 – 14:20 Lunch & poster session
Chair: Andre Koit
14:20 – 14:50 Invited speaker: Jakub Rohlena – Reactivation of dihydroorotate dehydrogenase by respiration restores tumor growth of mitochondrial DNA-depleted cancer cells
14:50 – 15:20 Invited speaker: Malgorzata Tokarska-Schlattner – Doxorubicin cardiotoxicity: mechanistic insight by phosphoproteomics
15:20 – 15:50 Invited speaker: Jukka Kallijärvi – A novel spontaneous CYTB variant exacerbates respiratory chain complex III deficiency in mice
15:50 – 16:10 Kattri-Liis Eskla – Hypothermia augments stress response in mammalian cells
16:10 – 16:40 Jayasimman Rajendran – Alternative oxidase prevents lethal mitochondrial cardiomyopathy by restoring respiration
16:40 – 16:45 Poster Awards
16:45 Closing
