Project Title: Exploring the molecular mechanisms behind the effects of physical exercise on breast cancer prevention (CancerBeat)

Funding: EEA and Norway Grants 2014-2021

Project No EEA-RESEARCH-164

Period:01.05.2021-30.04.2024

Project promoter: Latvian Biomedical Research and Study Centre

 

Partners:  Oslo University Hospital; National Institute of Chemical Physics and Biophysics, Estonia; National Cancer Institute, Lithuania; Latvian Academy of Sport Education

Project Costs: EUR 1 000 000.00

Principle Investigator: Dr. Bio. Aija Linē

Project aim (summary): It is well known that physical activity can prevent cancer development, but the molecular mechanisms behind these effects are poorly understood. During exercise, extracellular vesicles (EVs) are released into the circulation and mediate tissue crosstalk with potential effects on tumour cells and the immune tumour microenvironment. The overall aim of CancerBeat is to characterise the molecular cargo of exercise-induced EVs and explore their effects on breast cancer (BC) progression in vitro and in vivo.

Expected results of the project: It is planned to prepare 8 scientific publications, to present the results at 9 international conferences during the project.

 

More information on EEA and Norwegian grants is available at: www.norwaygrants.lv un www.eeagrants.lv.

Programme: Research and Education, Baltic research Programme