{"id":3566,"date":"2019-05-02T19:11:17","date_gmt":"2019-05-02T16:11:17","guid":{"rendered":"http:\/\/kbfi.ee\/?page_id=3566"},"modified":"2019-05-16T15:39:55","modified_gmt":"2019-05-16T12:39:55","slug":"masters-student-needed-in-researching-electric-fields-in-dna","status":"publish","type":"page","link":"https:\/\/kbfi.ee\/en\/chemical-physics\/research\/nonlinear-spectroscopy\/masters-student-needed-in-researching-electric-fields-in-dna\/","title":{"rendered":"Masters Student needed in researching electric fields in DNA"},"content":{"rendered":"<p><strong>Masters Student needed in researching electric fields in DNA<\/strong><\/p>\n<p>Deoxyribonucleic Acid (DNA) is a complex biomolecule that serves as long-term information storage in all living organisms. The remarkable longevity of DNA stems from the chemical stability of the individual nucleosides, but also from many interactions between sequential nucleosides as well as larger structures that pack and protect this sequence. Although these large-scale effects have been observed, the affects they have on the stability of DNA is not well understood, particularly in terms of the electric forces that hold the extended structure together, which act over scales of approximately 1-100 nanometers. Our lab at Keemilise ja Bioloogilise F\u00fc\u00fcsika Instituut, headed by Prof. Aleksander Rebane, has developed \u201cMolecular Voltmeter\u201d probes<sup>1<\/sup> capable of measuring nanoscale electric fields using the nonlinear optical technique known as two-photon absorption spectroscopy. These probes can be inserted into DNA, and we plan to use them to measure the electric field between nucleosides.<\/p>\n<p>The Masters student will be handling DNA samples, preparing buffer solutions, assisting in the process of intercalating probes, and learning the techniques of two-photon absorption spectroscopy. Along with research tasks which they can use for their Masters thesis, they will have the opportunity to attend international conferences and be involved in publishing results in scientific journals.\u00a0Monthly scholarship is provided!<\/p>\n<p style=\"text-align: left;\"><strong>We are looking for someone who:<img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-3598 lazyload\" data-src=\"https:\/\/kbfi.ee\/wp-content\/uploads\/2019\/05\/Molecule_plus_DNA_transparent-201x300.png\" alt=\"\" width=\"275\" height=\"410\" data-srcset=\"https:\/\/kbfi.ee\/wp-content\/uploads\/2019\/05\/Molecule_plus_DNA_transparent-201x300.png 201w, https:\/\/kbfi.ee\/wp-content\/uploads\/2019\/05\/Molecule_plus_DNA_transparent.png 465w\" data-sizes=\"(max-width: 275px) 100vw, 275px\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 275px; --smush-placeholder-aspect-ratio: 275\/410;\" \/><noscript><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-3598\" src=\"https:\/\/kbfi.ee\/wp-content\/uploads\/2019\/05\/Molecule_plus_DNA_transparent-201x300.png\" alt=\"\" width=\"275\" height=\"410\" srcset=\"https:\/\/kbfi.ee\/wp-content\/uploads\/2019\/05\/Molecule_plus_DNA_transparent-201x300.png 201w, https:\/\/kbfi.ee\/wp-content\/uploads\/2019\/05\/Molecule_plus_DNA_transparent.png 465w\" sizes=\"(max-width: 275px) 100vw, 275px\" \/><\/noscript> <\/strong><\/p>\n<ul>\n<li><strong>Has worked with DNA in a Lab or other setting<\/strong><\/li>\n<li><strong>Has some knowledge of chemistry<\/strong><\/li>\n<li><strong>Would be interested in high powered lasers<\/strong><\/li>\n<li><strong>Is proficient in English<\/strong><\/li>\n<li><strong>Can give a great high five, because teamwork is key<\/strong><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-3600 lazyload\" data-src=\"https:\/\/kbfi.ee\/wp-content\/uploads\/2019\/05\/RUphen2dppz_transparent-300x264.png\" alt=\"\" width=\"216\" height=\"190\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 216px; --smush-placeholder-aspect-ratio: 216\/190;\" \/><noscript><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-3600\" src=\"https:\/\/kbfi.ee\/wp-content\/uploads\/2019\/05\/RUphen2dppz_transparent-300x264.png\" alt=\"\" width=\"216\" height=\"190\" \/><\/noscript><\/p>\n<p>&nbsp;<\/p>\n<p>References:<\/p>\n<ol>\n<li>Rebane, A. <em>et al.<\/em> Two-Photon Voltmeter for Measuring a Molecular Electric Field. <em>Angew. Chem. Int. Ed.<\/em> <strong>54<\/strong>, 7582\u20137586 (2015).<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>Contact:<\/p>\n<p>Stark Charles,\u00a0<a href=\"mailto:CharStark@gmail.com\">charstark@gmail.com<\/a><\/p>\n<p>prof. Aleksander Rebane,\u00a0<a href=\"mailto:arebane@montana.edu\">arebane@montana.edu<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Masters Student needed in researching electric fields in DNA Deoxyribonucleic Acid (DNA) is a complex biomolecule that serves as long-term information storage in all living organisms. The <a class=\"read-more\" href=\"https:\/\/kbfi.ee\/en\/chemical-physics\/research\/nonlinear-spectroscopy\/masters-student-needed-in-researching-electric-fields-in-dna\/\"><\/a><\/p>\n","protected":false},"author":26,"featured_media":0,"parent":1446,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-3566","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/kbfi.ee\/en\/wp-json\/wp\/v2\/pages\/3566"}],"collection":[{"href":"https:\/\/kbfi.ee\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/kbfi.ee\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/kbfi.ee\/en\/wp-json\/wp\/v2\/users\/26"}],"replies":[{"embeddable":true,"href":"https:\/\/kbfi.ee\/en\/wp-json\/wp\/v2\/comments?post=3566"}],"version-history":[{"count":0,"href":"https:\/\/kbfi.ee\/en\/wp-json\/wp\/v2\/pages\/3566\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/kbfi.ee\/en\/wp-json\/wp\/v2\/pages\/1446"}],"wp:attachment":[{"href":"https:\/\/kbfi.ee\/en\/wp-json\/wp\/v2\/media?parent=3566"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}